October - December 2014

Vol. 5 - 4



Post-exposure Prophylaxis for Occupational Exposure to hiv

(Ashok Aggarwal, Sathyajith Naik, Satyaki Arora, Shivangi Sharma)



Post-exposure prophylaxis (PEP) is a medical response given to prevent the transmission of pathogens after potential exposure. The PEP for human immunodeficiency virus (HIV) refers to a set of comprehensive services to prevent HIV infection in exposed individuals where the exposure can be occupational or nonoccupational (nPEP). Although the principles of exposure management remain unchanged, recommended HIV PEP regimens have been changed. This review emphasizes adherence to HIV PEP when it is indicated for an exposure, expert consultation in management of exposures, follow-up of exposed workers to improve adherence in PEP and monitoring
of adverse events, including seroconversion. To ensure timely post-exposure management and administration of HIV postexposure prophylaxis, clinicians should consider occupational exposures as urgent medical concerns.

Key words:HIV, Post-exposure prophylaxis, Antiviral drugs, Occupational exposure, HCP, HCW..